Our Research
Significance of the Research
Nano-drug delivery systems are potentially imperative for various reasons, such as target specificity, accumulation in the tumor microenvironment, multiple drug loading ability, and tailor-made sustained drug release. Even though the use of various nanoparticles in drug delivery systems is diverse and prompt in the current decade, the concern about the toxic impact of nanoparticles on biological systems is minimal. Therefore, we introduce non-toxic, biocompatible, and photoluminescent nanoparticle carbon dots as a nano-carrier for various diseases such as tumors, bone, and neurodegenerative diseases. C-dots are proven to be promising in drug delivery systems, especially due to their smaller size (1-10 nm) and multiple drug loading efficacy.
The development of multidrug resistance is an increasing challenge in cancer therapy. Hence, the ability to load multiple drugs at once on a single nano-carrier is highly essential. Despite the cancer therapy, the multiple drug loading ability is equally important in Alzheimer’s Disease (AD) treatments. The prominent hallmark feature of AD is the amyloid cascade, while the non-amyloid hypotheses also contribute to the disease’s severeness. However, to reduce AD’s risk, the amyloid and non-amyloid hypotheses should be treated at once. Hence, we research for carbon dots based combo systems to treat amyloid and non-amyloid hypothesis at once. Moreover, the small particle size of carbon dots has promisingly supported the penetration of harmless cell membrane or blood-brain barrier. Carbon dots based nano-models are being used as bio-imaging tools to castoff calcium-rich environments such as bone cancers or bone cracks.
The development of multidrug resistance is an increasing challenge in cancer therapy. Hence, the ability to load multiple drugs at once on a single nano-carrier is highly essential. Despite the cancer therapy, the multiple drug loading ability is equally important in Alzheimer’s Disease (AD) treatments. The prominent hallmark feature of AD is the amyloid cascade, while the non-amyloid hypotheses also contribute to the disease’s severeness. However, to reduce AD’s risk, the amyloid and non-amyloid hypotheses should be treated at once. Hence, we research for carbon dots based combo systems to treat amyloid and non-amyloid hypothesis at once. Moreover, the small particle size of carbon dots has promisingly supported the penetration of harmless cell membrane or blood-brain barrier. Carbon dots based nano-models are being used as bio-imaging tools to castoff calcium-rich environments such as bone cancers or bone cracks.
